The evolutionary origins of anti-phage membrane proteins using bioinformatics and biochemistry
University of Rochester - O'Connell Lab
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Posted 27 days ago
5 hours/week
In-Person, Remote, Hybrid
Class of 2026, 2025, 2024, 2023
Decision by 02/28/2025
Natural and Biomedical Sciences
Biological Sciences: Biochemistry, Biological Sciences: Computational Biology, Biology
We study proteins that bacteria use to protect themselves from bacteriophages, a type of virus that only infects microbes. The lab’s research began with explorations of CRISPR-Cas13 systems, but in recent years, this has expanded to focus on the evolution of antiphage membrane proteins. We’re looking for an undergraduate who can help to expand our understanding of the evolutionary origins of these proteins using bioinformatics and biochemistry. Prior coding experience is recommended
Desired Experience
Prior coding experience is highly recommended
About the Mentor
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Mitchell O'Connell

Professor
Biological Sciences: Biochemistry, Biological Sciences: Computational Biology mitchell_oconnell@urmc.rochester.edu
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